Neuregulin-1 (NRG-1) and its susceptibility to schizophrenia: a case-control study and meta-analysis.

نویسندگان

  • Han Chern Loh
  • Pek Yee Tang
  • Shiau Foon Tee
  • Tze Jen Chow
  • Chee Yen Choong
  • Shen Yang Lim
  • Hoi Sen Yong
چکیده

Neuregulin-1 is widely investigated due to its hypothesised association with schizophrenia. Single-nucleotide polymorphisms rs764059, rs2954041 and rs3924999 were investigated (417 patients with schizophrenia and 429 controls). We failed to demonstrate a significant association between rs2954041 and rs3924999 with schizophrenia in the three ethnic groups studied (Malay, Chinese, and Indian), while rs764059 was found to be monomorphic.

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عنوان ژورنال:
  • Psychiatry research

دوره 208 2  شماره 

صفحات  -

تاریخ انتشار 2013